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BMCBI
2008
126views more  BMCBI 2008»
13 years 9 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
BMCBI
2008
118views more  BMCBI 2008»
13 years 9 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
BMCBI
2008
135views more  BMCBI 2008»
13 years 9 months ago
Functional site prediction selects correct protein models
Background: The prediction of protein structure can be facilitated by the use of constraints based on a knowledge of functional sites. Without this information it is still possibl...
Vijayalakshmi Chelliah, William R. Taylor
CORR
2010
Springer
146views Education» more  CORR 2010»
13 years 9 months ago
Active Learning for Hidden Attributes in Networks
In many networks, vertices have hidden attributes that are correlated with the network's topology. For instance, in social networks, people are more likely to be friends if t...
Xiaoran Yan, Yaojia Zhu, Jean-Baptiste Rouquier, C...
BMCBI
2006
135views more  BMCBI 2006»
13 years 9 months ago
TF Target Mapper: A BLAST search tool for the identification of Transcription Factor target genes
Background: In the current era of high throughput genomics a major challenge is the genome-wide identification of target genes for specific transcription factors. Chromatin immuno...
Sebastiaan Horsman, Michael J. Moorhouse, Victor C...
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