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BMCBI
2005
13 years 8 months ago
2005
Background: We present a biological data warehouse called Atlas that locally stores and integrates biological sequences, molecular interactions, homology information, functional a...
BMCBI
2005
13 years 8 months ago
2005
Background: Protein domains have long been an ill-defined concept in biology. They are generally described as autonomous folding units with evolutionary and functional independenc...
BMCBI
2005
13 years 8 months ago
2005
Background: In the context of the BioCreative competition, where training data were very sparse, we investigated two complementary tasks: 1) given a Swiss-Prot triplet, containing...
BMCBI
2005
13 years 8 months ago
2005
Background: The SH3 domain family is one of the most representative and widely studied cases of so-called Peptide Recognition Modules (PRM). The polyproline II motif PxxP that gen...
BMCBI
2005
13 years 8 months ago
2005
Background: The advent of the technology of DNA microarrays constitutes an epochal change in the classification and discovery of different types of cancer because the information ...