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BMCBI
2011
13 years 5 months ago
OrthoInspector: comprehensive orthology analysis and visual exploration
Background: The accurate determination of orthology and inparalogy relationships is essential for comparative sequence analysis, functional gene annotation and evolutionary studie...
Benjamin Linard, Julie D. Thompson, Olivier Poch, ...
BMCBI
2011
13 years 5 months ago
Pathway-based analysis using reduced gene subsets in genome-wide association studies
Background: Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to s...
Jingyuan Zhao, Simone Gupta, Mark Seielstad, Jianj...
BMCBI
2011
13 years 5 months ago
Logical Development of the Cell Ontology
Background: The Cell Ontology (CL) is an ontology for the representation of in vivo cell types. As biological ontologies such as the CL grow in complexity, they become increasingl...
Terrence F. Meehan, Anna Maria Masci, Amina Abdull...
BMCBI
2011
13 years 5 months ago
Revision history aware repositories of computational models of biological systems
Background: Building repositories of computational models of biological systems ensures that published models are available for both education and further research, and can provid...
Andrew K. Miller, Tommy Yu, Randall Britten, Mike ...
BMCBI
2011
13 years 5 months ago
Multivariate analysis of microarray data: differential expression and differential connection
Background: Typical analysis of microarray data ignores the correlation between gene expression values. In this paper we present a model for microarray data which specifically all...
Harri T. Kiiveri