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EKAW
2008
Springer
13 years 10 months ago
Principles for Knowledge Engineering on the Web
With the advent of the Web and the efforts towards a Semantic Web the nature of knowledge engineering has changed drastically. In this position paper we propose four principles fo...
Guus Schreiber
BMCBI
2010
136views more  BMCBI 2010»
13 years 8 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
BMCBI
2008
118views more  BMCBI 2008»
13 years 8 months ago
Virtual screening of GPCRs: An in silico chemogenomics approach
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Laurent Jacob, Brice Hoffmann, Véronique St...
BMCBI
2006
202views more  BMCBI 2006»
13 years 8 months ago
DWARF - a data warehouse system for analyzing protein families
Background: The emerging field of integrative bioinformatics provides the tools to organize and systematically analyze vast amounts of highly diverse biological data and thus allo...
Markus Fischer, Quan K. Thai, Melanie Grieb, J&uum...
INFORMATICALT
2006
89views more  INFORMATICALT 2006»
13 years 8 months ago
Investigation of Examples of E-Education Environment for Scientific Collaboration and Distance Graduate Studies, Part 1
The objective is to investigate two emerging information technologies in graduate studies and scientific cooperation. Internet is the first technology. The open source is the secon...
Jonas Mockus