With the advent of the Web and the efforts towards a Semantic Web the nature of knowledge engineering has changed drastically. In this position paper we propose four principles fo...
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
Background: The emerging field of integrative bioinformatics provides the tools to organize and systematically analyze vast amounts of highly diverse biological data and thus allo...
Markus Fischer, Quan K. Thai, Melanie Grieb, J&uum...
The objective is to investigate two emerging information technologies in graduate studies and scientific cooperation. Internet is the first technology. The open source is the secon...