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RECOMB
2005
Springer
14 years 7 months ago
Very Low Power to Detect Asymmetric Divergence of Duplicated Genes
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
Cathal Seoighe, Konrad Scheffler
ALMOB
2008
160views more  ALMOB 2008»
13 years 7 months ago
Syntenator: Multiple gene order alignments with a gene-specific scoring function
Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
Christian Rödelsperger, Christoph Dieterich
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
14 years 26 days ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
BMCBI
2006
169views more  BMCBI 2006»
13 years 7 months ago
Assessing protein similarity with Gene Ontology and its use in subnuclear localization prediction
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Zhengdeng Lei, Yang Dai
ICMLA
2008
13 years 9 months ago
Comprehensible Models for Predicting Molecular Interaction with Heart-Regulating Genes
When using machine learning for in silico modeling, the goal is normally to obtain highly accurate predictive models. Often, however, models should also bring insights into intere...
Cecilia Sönströd, Ulf Johansson, Ulf Nor...