Sciweavers

170 search results - page 16 / 34
» Information-based methods for predicting gene function from ...
Sort
View
JIB
2006
220views more  JIB 2006»
13 years 7 months ago
An assessment of machine and statistical learning approaches to inferring networks of protein-protein interactions
Protein-protein interactions (PPI) play a key role in many biological systems. Over the past few years, an explosion in availability of functional biological data obtained from hi...
Fiona Browne, Haiying Wang, Huiru Zheng, Francisco...
RECOMB
2003
Springer
14 years 8 months ago
An integrated probabilistic model for functional prediction of proteins
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Minghua Deng, Ting Chen, Fengzhu Sun
GCB
2007
Springer
161views Biometrics» more  GCB 2007»
14 years 1 months ago
High-Precision Function Prediction using Conserved Interactions
: The recent availability of large data sets of protein- protein-interactions (PPIs) from various species offers new opportunities for functional genomics and proteomics. We descri...
Samira Jaeger, Ulf Leser
BMCBI
2008
126views more  BMCBI 2008»
13 years 7 months ago
c-REDUCE: Incorporating sequence conservation to detect motifs that correlate with expression
Background: Computational methods for characterizing novel transcription factor binding sites search for sequence patterns or "motifs" that appear repeatedly in genomic ...
Katerina Kechris, Hao Li
BIOINFORMATICS
2007
195views more  BIOINFORMATICS 2007»
13 years 7 months ago
Context-dependent clustering for dynamic cellular state modeling of microarray gene expression
Motivation: High-throughput expression profiling allows researchers to study gene activities globally. Genes with similar expression profiles are likely to encode proteins that ma...
Shinsheng Yuan, Ker-Chau Li