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ESANN
2003
13 years 8 months ago
Approximately unbiased estimation of conditional variance in heteroscedastic kernel ridge regression
In this paper we extend a form of kernel ridge regression for data characterised by a heteroscedastic noise process (introduced in Foxall et al. [1]) in order to provide approxima...
Gavin C. Cawley, Nicola L. C. Talbot, Robert J. Fo...
BMCBI
2010
130views more  BMCBI 2010»
13 years 6 months ago
Amino acid "little Big Bang": Representing amino acid substitution matrices as dot products of Euclidian vectors
Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
Karel Zimmermann, Jean-François Gibrat
BMCBI
2010
125views more  BMCBI 2010»
13 years 6 months ago
Large-scale prediction of protein-protein interactions from structures
Background: The prediction of protein-protein interactions is an important step toward the elucidation of protein functions and the understanding of the molecular mechanisms insid...
Martial Hue, Michael Riffle, Jean-Philippe Vert, W...
BMCBI
2010
135views more  BMCBI 2010»
13 years 6 months ago
GIGA: a simple, efficient algorithm for gene tree inference in the genomic age
Background: Phylogenetic relationships between genes are not only of theoretical interest: they enable us to learn about human genes through the experimental work on their relativ...
Paul D. Thomas
BMCBI
2010
102views more  BMCBI 2010»
13 years 6 months ago
Peptide binding predictions for HLA DR, DP and DQ molecules
Background: MHC class II binding predictions are widely used to identify epitope candidates in infectious agents, allergens, cancer and autoantigens. The vast majority of predicti...
Peng Wang, John Sidney, Yohan Kim, Alessandro Sett...