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BMCBI
2010
185views more  BMCBI 2010»
13 years 10 months ago
ABCtoolbox: a versatile toolkit for approximate Bayesian computations
Background: The estimation of demographic parameters from genetic data often requires the computation of likelihoods. However, the likelihood function is computationally intractab...
Daniel Wegmann, Christoph Leuenberger, Samuel Neue...
BMCBI
2010
151views more  BMCBI 2010»
13 years 10 months ago
CCRaVAT and QuTie - enabling analysis of rare variants in large-scale case control and quantitative trait association studies
Background: Genome-wide association studies have been successful in finding common variants influencing common traits. However, these associations only account for a fraction of t...
Robert Lawrence, Aaron G. Day-Williams, Katherine ...
BMCBI
2008
125views more  BMCBI 2008»
13 years 10 months ago
SNPLims: a data management system for genome wide association studies
Background: Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample. The ava...
Alessandro Orro, Guia Guffanti, Erika Salvi, Fabio...
CCGRID
2009
IEEE
14 years 4 months ago
BLAST Application with Data-Aware Desktop Grid Middleware
—There exists numerous Grid middleware to develop and execute programs on the computational Grid, but they still require intensive work from their users. BitDew is made to facili...
Haiwu He, Gilles Fedak, Bing Tang, Franck Cappello
ICALP
2001
Springer
14 years 2 months ago
Permutation Editing and Matching via Embeddings
Abstract. If the genetic maps of two species are modelled as permutations of (homologous) genes, the number of chromosomal rearrangements in the form of deletions, block moves, inv...
Graham Cormode, S. Muthukrishnan, Süleyman Ce...