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BMCBI
2006
102views more  BMCBI 2006»
13 years 7 months ago
MycoperonDB: a database of computationally identified operons and transcriptional units in Mycobacteria
Background: A key post genomics challenge is to identify how genes in an organism come together and perform physiological functions. An important first step in this direction is t...
Sarita Ranjan, Ranjit Kumar Gundu, Akash Ranjan
BMCBI
2006
94views more  BMCBI 2006»
13 years 7 months ago
Fly-DPI: database of protein interactomes for D. melanogaster in the approach of systems biology
Background: Proteins control and mediate many biological activities of cells by interacting with other protein partners. This work presents a statistical model to predict protein ...
Chung-Yen Lin, Shu-Hwa Chen, Chi-Shiang Cho, Chia-...
BMCBI
2006
155views more  BMCBI 2006»
13 years 7 months ago
A powerful method for detecting differentially expressed genes from GeneChip arrays that does not require replicates
Background: Studies of differential expression that use Affymetrix GeneChip arrays are often carried out with a limited number of replicates. Reasons for this include financial co...
Anne-Mette K. Hein, Sylvia Richardson
BMCBI
2006
149views more  BMCBI 2006»
13 years 7 months ago
HeatMapper: powerful combined visualization of gene expression profile correlations, genotypes, phenotypes and sample characteri
Background: Accurate interpretation of data obtained by unsupervised analysis of large scale expression profiling studies is currently frequently performed by visually combining s...
Roel G. W. Verhaak, Mathijs A. Sanders, Maarten A....
BMCBI
2006
144views more  BMCBI 2006»
13 years 7 months ago
methBLAST and methPrimerDB: web-tools for PCR based methylation analysis
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...