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BMCBI
2010
126views more  BMCBI 2010»
13 years 4 months ago
Systematic integration of experimental data and models in systems biology
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...
BMCBI
2008
202views more  BMCBI 2008»
13 years 7 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
DILS
2009
Springer
14 years 1 months ago
Integration of Full-Coverage Probabilistic Functional Networks with Relevance to Specific Biological Processes
Probabilistic functional integrated networks are powerful tools with which to draw inferences from high-throughput data. However, network analyses are generally not tailored to spe...
Katherine James, Anil Wipat, Jennifer Hallinan
JCB
2006
185views more  JCB 2006»
13 years 7 months ago
A Probabilistic Methodology for Integrating Knowledge and Experiments on Biological Networks
Biological systems are traditionally studied by focusing on a specific subsystem, building an intuitive model for it, and refining the model using results from carefully designed ...
Irit Gat-Viks, Amos Tanay, Daniela Raijman, Ron Sh...
BICOB
2010
Springer
14 years 5 days ago
Biological Relevance Detection via Network Dynamic Analysis
Most existing approaches for gene selection are based on evaluating the statistical relevance. However, there are remarkable discrepancies between statistical relevance and biolog...
Zheng Zhao, Huan Liu, Jiangxin Wang, Yung Chang