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BMCBI
2010
162views more  BMCBI 2010»
13 years 10 months ago
Moara: a Java library for extracting and normalizing gene and protein mentions
Background: Gene/protein recognition and normalization are important preliminary steps for many biological text mining tasks, such as information retrieval, protein-protein intera...
Mariana L. Neves, José María Carazo,...
BMCBI
2010
214views more  BMCBI 2010»
13 years 10 months ago
AutoSOME: a clustering method for identifying gene expression modules without prior knowledge of cluster number
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...
Aaron M. Newman, James B. Cooper
BMCBI
2010
154views more  BMCBI 2010»
13 years 10 months ago
An eScience-Bayes strategy for analyzing omics data
Background: The omics fields promise to revolutionize our understanding of biology and biomedicine. However, their potential is compromised by the challenge to analyze the huge da...
Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg
BIOINFORMATICS
2008
106views more  BIOINFORMATICS 2008»
13 years 10 months ago
Small RNA gene identification and mRNA target predictions in bacteria
Motivation: Bacterial small ribonucleic acids (sRNAs) that are not ribosomal and transfer or messenger RNAs were initially identified in the sixties whereas their molecular functi...
Christophe Pichon, Brice Felden
BMCBI
2010
93views more  BMCBI 2010»
13 years 10 months ago
Hybridization thermodynamics of NimbleGen Microarrays
Background: While microarrays are the predominant method for gene expression profiling, probe signal variation is still an area of active research. Probe signal is sequence depend...
Ulrike Mückstein, Germán G. Leparc, Al...