Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Background: Oligonucleotide frequencies were shown to be conserved signatures for bacterial genomes, however, the underlying constraints have yet not been resolved in detail. In t...
Pottmann et al. propose an iterative optimization scheme for approximating a target curve with a B-spline curve based on square distance minimization, or SDM. The main advantage o...
? Network analysis, an area of mathematical sociology and anthropology crucial to the linking of theory and observation, developed dramatically in recent decades. These development...