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» Interaction Analysis in Aspect-Oriented Models
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JCB
2007
144views more  JCB 2007»
13 years 8 months ago
Statistical Estimation of Statistical Mechanical Models: Helix-Coil Theory and Peptide Helicity Prediction
Analysis of biopolymer sequences and structures generally adopts one of two approaches: use of detailed biophysical theoretical models of the system with experimentally-determined...
Scott C. Schmidler, Joseph E. Lucas, Terrence G. O...
BMCBI
2011
12 years 11 months ago
A hierarchical Bayesian network approach for linkage disequilibrium modeling and data-dimensionality reduction prior to genome-w
Background: Discovering the genetic basis of common genetic diseases in the human genome represents a public health issue. However, the dimensionality of the genetic data (up to 1...
Raphael Mourad, Christine Sinoquet, Philippe Leray
CONCUR
2007
Springer
14 years 2 months ago
Rule-Based Modelling of Cellular Signalling
Abstract. Modelling is becoming a necessity in studying biological signalling pathways, because the combinatorial complexity of such systems rapidly overwhelms intuitive and qualit...
Vincent Danos, Jérôme Feret, Walter F...
CSB
2003
IEEE
14 years 1 months ago
LOGOS: a modular Bayesian model for de novo motif detection
The complexity of the global organization and internal structures of motifs in higher eukaryotic organisms raises significant challenges for motif detection techniques. To achiev...
Eric P. Xing, Wei Wu, Michael I. Jordan, Richard M...
JKM
2007
213views more  JKM 2007»
13 years 8 months ago
A systems-based dynamic knowledge transfer capacity model
Purpose – The purpose of this paper is twofold: to understand how recent developments in systems thinking and social construction can influence understanding of knowledge trans...
Robert Parent, Mario Roy, Denis St-Jacques