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BMCBI
2010
149views more  BMCBI 2010»
13 years 10 months ago
RuleMonkey: software for stochastic simulation of rule-based models
Background: The system-level dynamics of many molecular interactions, particularly protein-protein interactions, can be conveniently represented using reaction rules, which can be...
Joshua Colvin, Michael I. Monine, Ryan N. Gutenkun...
BMCBI
2008
145views more  BMCBI 2008»
13 years 10 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2008
132views more  BMCBI 2008»
13 years 10 months ago
Clustering ionic flow blockade toggles with a Mixture of HMMs
Background: Ionic current blockade signal processing, for use in nanopore detection, offers a promising new way to analyze single molecule properties with potential implications f...
Alexander G. Churbanov, Stephen Winters-Hilt
CGF
2010
144views more  CGF 2010»
13 years 10 months ago
Dynamic Multi-View Exploration of Shape Spaces
Statistical shape modeling is a widely used technique for the representation and analysis of the shapes and shape variations present in a population. A statistical shape model mod...
Stef Busking, Charl P. Botha, Frits H. Post
BMCBI
2006
128views more  BMCBI 2006»
13 years 10 months ago
Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...