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BMCBI
2006
145views more  BMCBI 2006»
15 years 2 months ago
GEM System: automatic prototyping of cell-wide metabolic pathway models from genomes
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
Kazuharu Arakawa, Yohei Yamada, Kosaku Shinoda, Yo...
105
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BMCBI
2006
108views more  BMCBI 2006»
15 years 2 months ago
Probe set algorithms: is there a rational best bet?
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
Jinwook Seo, Eric P. Hoffman
103
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BMCBI
2006
129views more  BMCBI 2006»
15 years 2 months ago
A literature-based similarity metric for biological processes
Background: Recent analyses in systems biology pursue the discovery of functional modules within the cell. Recognition of such modules requires the integrative analysis of genome-...
Monica Chagoyen, Pedro Carmona-Saez, Concha Gil, J...
114
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BMCBI
2006
75views more  BMCBI 2006»
15 years 2 months ago
A machine learning strategy to identify candidate binding sites in human protein-coding sequence
Background: The splicing of RNA transcripts is thought to be partly promoted and regulated by sequences embedded within exons. Known sequences include binding sites for SR protein...
Thomas Down, Bernard Leong, Tim J. P. Hubbard
160
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CAD
2006
Springer
15 years 2 months ago
On visual similarity based 2D drawing retrieval
A large amount of 2D drawings have been produced in engineering fields. To reuse and share the available drawings efficiently, we propose two methods in this paper, namely 2.5D sp...
Jiantao Pu, Karthik Ramani
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