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JCB
2002
131views more  JCB 2002»
13 years 7 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
ML
1998
ACM
115views Machine Learning» more  ML 1998»
13 years 7 months ago
Pharmacophore Discovery Using the Inductive Logic Programming System PROGOL
This paper is a case study of a machine aided knowledge discovery process within the general area of drug design. More speci cally, the paper describes a sequence of experiments in...
Paul W. Finn, Stephen Muggleton, David Page, Ashwi...
NAR
2007
131views more  NAR 2007»
13 years 7 months ago
Snap: an integrated SNP annotation platform
Snap (Single Nucleotide Polymorphism Annotation Platform) is a server designed to comprehensively analyze single genes and relationships between genes basing on SNPs in the human ...
Shengting Li, Lijia Ma, Heng Li, Søren Vang...
BIOCOMP
2010
13 years 5 months ago
A Model Reduction Technique for Stochastic Biochemical Kinetics
Abstract-- Modeling the intermolecular reactions in a single cell is a critical problem in computational biology. Biochemical reaction systems often involve species in both low and...
Silvana Ilie, Ekaterina Kudashkina
NAACL
2010
13 years 5 months ago
Joint Inference for Knowledge Extraction from Biomedical Literature
Knowledge extraction from online repositories such as PubMed holds the promise of dramatically speeding up biomedical research and drug design. After initially focusing on recogni...
Hoifung Poon, Lucy Vanderwende