Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
Background: Gene/protein recognition and normalization are important preliminary steps for many biological text mining tasks, such as information retrieval, protein-protein intera...
Background: Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing met...
Norman E. Davey, Richard J. Edwards, Denis C. Shie...
Background: The estimation of demographic parameters from genetic data often requires the computation of likelihoods. However, the likelihood function is computationally intractab...
Daniel Wegmann, Christoph Leuenberger, Samuel Neue...
Background: Clustering the information content of large high-dimensional gene expression datasets has widespread application in "omics" biology. Unfortunately, the under...