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BMCBI
2010
115views more  BMCBI 2010»
13 years 10 months ago
Multiconstrained gene clustering based on generalized projections
Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
BMCBI
2010
86views more  BMCBI 2010»
13 years 10 months ago
An automatic method for identifying surface proteins in bacteria: SLEP
Background: Bacterial infections represent a global health challenge. The identification of novel antibacterial targets for both therapy and vaccination is needed on a constant ba...
Emanuela Giombini, Massimiliano Orsini, Danilo Car...
BMCBI
2010
146views more  BMCBI 2010»
13 years 10 months ago
Revealing and avoiding bias in semantic similarity scores for protein pairs
Background: Semantic similarity scores for protein pairs are widely applied in functional genomic researches for finding functional clusters of proteins, predicting protein functi...
Jing Wang 0004, Xianxiao Zhou, Jing Zhu, Chenggui ...
BMCBI
2010
122views more  BMCBI 2010»
13 years 10 months ago
Ovarian cancer classification based on dimensionality reduction for SELDI-TOF data
Background: Recent advances in proteomics technologies such as SELDI-TOF mass spectrometry has shown promise in the detection of early stage cancers. However, dimensionality reduc...
Kai-Lin Tang, Tong-Hua Li, Wen-Wei Xiong, Kai Chen
BMCBI
2010
84views more  BMCBI 2010»
13 years 10 months ago
Word add-in for ontology recognition: semantic enrichment of scientific literature
Background: In the current era of scientific research, efficient communication of information is paramount. As such, the nature of scholarly and scientific communication is changi...
J. Lynn Fink, Pablo Fernicola, Rahul Chandran, Sav...