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BMCBI
2010
13 years 10 months ago
2010
Background: This paper compares the most common digital signal processing methods of exon prediction in eukaryotes, and also proposes a technique for noise suppression in exon pre...
BMCBI
2010
13 years 10 months ago
2010
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
BMCBI
2008
13 years 10 months ago
2008
Background: DNA methylation is an important epigenetic modification of the genome. Abnormal DNA methylation may result in silencing of tumor suppressor genes and is common in a va...
BMCBI
2008
13 years 10 months ago
2008
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
BMCBI
2010
13 years 10 months ago
2010
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...