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» Intrusion Detection: A Bioinformatics Approach
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BMCBI
2006
165views more  BMCBI 2006»
13 years 11 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
DATAMINE
2007
135views more  DATAMINE 2007»
13 years 10 months ago
Experiencing SAX: a novel symbolic representation of time series
Many high level representations of time series have been proposed for data mining, including Fourier transforms, wavelets, eigenwaves, piecewise polynomial models etc. Many researc...
Jessica Lin, Eamonn J. Keogh, Li Wei, Stefano Lona...
WABI
2009
Springer
142views Bioinformatics» more  WABI 2009»
14 years 5 months ago
Back-Translation for Discovering Distant Protein Homologies
Background: Frameshift mutations in protein-coding DNA sequences produce a drastic change in the resulting protein sequence, which prevents classic protein alignment methods from ...
Marta Gîrdea, Laurent Noé, Gregory Ku...
CSB
2003
IEEE
110views Bioinformatics» more  CSB 2003»
14 years 4 months ago
Statistical Inference for Well-ordered Structures in Nucleotide Sequences
Distinct, local structures are frequently correlated with functional RNA elements involved in posttranscriptional regulation of gene expression. Discovery of microRNAs (miRNAs) su...
Shu-Yun Le, Jih-H. Chen, Jacob V. Maizel
BMCBI
2010
201views more  BMCBI 2010»
13 years 11 months ago
Analysis of X-ray Structures of Matrix Metalloproteinases via Chaotic Map Clustering
Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
Ilenia Giangreco, Orazio Nicolotti, Angelo Carotti...