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144
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BMCBI
2011
14 years 9 months ago
Investigating the effect of paralogs on microarray gene-set analysis
Background: In order to interpret the results obtained from a microarray experiment, researchers often shift focus from analysis of individual differentially expressed genes to an...
Andre J. Faure, Cathal Seoighe, Nicola J. Mulder
156
Voted
BMCBI
2011
14 years 9 months ago
GCOD - GeneChip Oncology Database
Background: DNA microarrays have become a nearly ubiquitous tool for the study of human disease, and nowhere is this more true than in cancer. With hundreds of studies and thousan...
Fenglong Liu, Joseph White, Corina Antonescu, John...
130
Voted
BMCBI
2011
14 years 9 months ago
nocoRNAc: Characterization of non-coding RNAs in prokaryotes
Background: The interest in non-coding RNAs (ncRNAs) constantly rose during the past few years because of the wide spectrum of biological processes in which they are involved. Thi...
Alexander Herbig, Kay Nieselt
172
Voted
BMCBI
2011
14 years 9 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
BMCBI
2011
14 years 9 months ago
An Agent-Based Model to study the epidemiological and evolutionary dynamics of Influenza viruses
Background: Influenza A viruses exhibit complex epidemiological patterns in a number of mammalian and avian hosts. Understanding transmission of these viruses necessitates taking ...
Benjamin Roche, John M. Drake, Pejman Rohani
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