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BMCBI
2008
135views more  BMCBI 2008»
13 years 7 months ago
Fregene: Simulation of realistic sequence-level data in populations and ascertained samples
Background: FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows...
Marc Chadeau-Hyam, Clive J. Hoggart, Paul F. O'Rei...
BMCBI
2008
110views more  BMCBI 2008»
13 years 7 months ago
Enhancing the prediction of protein pairings between interacting families using orthology information
Background: It has repeatedly been shown that interacting protein families tend to have similar phylogenetic trees. These similarities can be used to predicting the mapping betwee...
José M. G. Izarzugaza, David de Juan, Carle...
CORR
2008
Springer
128views Education» more  CORR 2008»
13 years 7 months ago
A Fast Generic Sequence Matching Algorithm
A string matching--and more generally, sequence matching--algorithm is presented that has a linear worst-case computing time bound, a low worst-case bound on the number of compari...
David R. Musser, Gor V. Nishanov
AI
2006
Springer
13 years 7 months ago
Backward-chaining evolutionary algorithms
Starting from some simple observations on a popular selection method in Evolutionary Algorithms (EAs)--tournament selection--we highlight a previously-unknown source of inefficien...
Riccardo Poli, William B. Langdon
BMCBI
2006
101views more  BMCBI 2006»
13 years 7 months ago
How repetitive are genomes?
Background: Genome sequences vary strongly in their repetitiveness and the causes for this are still debated. Here we propose a novel measure of genome repetitiveness, the index o...
Bernhard Haubold, Thomas Wiehe