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BMCBI
2010
120views more  BMCBI 2010»
13 years 8 months ago
Optimal contact definition for reconstruction of Contact Maps
Background: Contact maps have been extensively used as a simplified representation of protein structures. They capture most important features of a protein's fold, being pref...
Jose M. Duarte, Rajagopal Sathyapriya, Henning Ste...
BMCBI
2010
102views more  BMCBI 2010»
13 years 8 months ago
SAMPLEX: Automatic mapping of perturbed and unperturbed regions of proteins and complexes
Background: The activity of proteins within the cell is characterized by their motions, flexibility, interactions or even the particularly intriguing case of partially unfolded st...
Mickaël Krzeminski, Karine Loth, Rolf Boelens...
BMCBI
2007
134views more  BMCBI 2007»
13 years 8 months ago
Automatic generation of 3D motifs for classification of protein binding sites
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...
BMCBI
2006
165views more  BMCBI 2006»
13 years 8 months ago
Improving the quality of protein structure models by selecting from alignment alternatives
Background: In the area of protein structure prediction, recently a lot of effort has gone into the development of Model Quality Assessment Programs (MQAPs). MQAPs distinguish hig...
Ingolf Sommer, Stefano Toppo, Oliver Sander, Thoma...
CSB
2005
IEEE
140views Bioinformatics» more  CSB 2005»
14 years 1 months ago
TPR Packing Analysis and 3D Modeling for the HAT Domain of Human Crooked Neck Protein
Human crooked neck protein (hcrn) containing 17 HAT or TPR repeats plays a role in pre-mRNA processing. Conserved residues in the TPR consensus sequence of 34 aa were found at hel...
Zhenglin Hou, Cunxi Wang, Odd-Arne Olsen