Motivation: The need for normalization in microarray experiments has been well documented in the literature. Currently, most analysis methods treat normalization and analysis as a...
Ann L. Oberg, Douglas W. Mahoney, Karla V. Ballman...
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...