A new method for detecting remote protein homologies is introduced and shown to perform well in classifying protein domains by SCOP superfamily. The method is a variant of support...
Background: The genomes of prokaryotes and lower eukaryotes display a very strong 11 bp periodic bias in the distribution of their nucleotides. This bias is present throughout a g...
In this paper we embed evolutionary computation into statistical learning theory. First, we outline the connection between large margin optimization and statistical learning and s...
Features in many real world applications such as Cheminformatics, Bioinformatics and Information Retrieval have complex internal structure. For example, frequent patterns mined fr...
Fisher linear discriminant analysis (FDA) and its kernel extension--kernel discriminant analysis (KDA)--are well known methods that consider dimensionality reduction and classific...
Zhihua Zhang, Guang Dai, Congfu Xu, Michael I. Jor...