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BMCBI
2010
111views more  BMCBI 2010»
13 years 7 months ago
Protein sequences classification by means of feature extraction with substitution matrices
Background: This paper deals with the preprocessing of protein sequences for supervised classification. Motif extraction is one way to address that task. It has been largely used ...
Rabie Saidi, Mondher Maddouri, Engelbert Mephu Ngu...
BMCBI
2008
106views more  BMCBI 2008»
13 years 7 months ago
SpliceCenter: A suite of web-based bioinformatic applications for evaluating the impact of alternative splicing on RT-PCR, RNAi,
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
Michael C. Ryan, Barry Zeeberg, Natasha J. Caplen,...
BMCBI
2008
99views more  BMCBI 2008»
13 years 7 months ago
Exhaustive prediction of disease susceptibility to coding base changes in the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are the most abundant form of genomic variation and can cause phenotypic differences between individuals, including diseases. Ba...
Vinayak Kulkarni, Mounir Errami, Robert Barber, Ha...
BMCBI
2006
124views more  BMCBI 2006»
13 years 7 months ago
HybGFS: a hybrid method for genome-fingerprint scanning
Background: Protein identification based on mass spectrometry (MS) has previously been performed using peptide mass fingerprinting (PMF) or tandem MS (MS/MS) database searching. H...
Kosaku Shinoda, Nozomu Yachie, Takeshi Masuda, Nao...
BMCBI
2006
131views more  BMCBI 2006»
13 years 7 months ago
Hybridization interactions between probesets in short oligo microarrays lead to spurious correlations
Background: Microarrays measure the binding of nucleotide sequences to a set of sequence specific probes. This information is combined with annotation specifying the relationship ...
Michal J. Okoniewski, Crispin J. Miller