Recently, spectral clustering (a.k.a. normalized graph cut) techniques have become popular for their potential ability at finding irregularlyshaped clusters in data. The input to...
Background: Development of high-throughput methods for measuring DNA interactions of transcription factors together with computational advances in short motif inference algorithms...
Similarity measures in many real applications generate indefinite similarity matrices. In this paper, we consider the problem of classification based on such indefinite similariti...
Abstract. Substitution matrices are at the heart of Bioinformatics: sequence alignment, database search, phylogenetic inference, protein family classication are based on Blosum, P...
Stephan Kitchovitch, Yuedong Song, Richard C. van ...
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...