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BMCBI
2010
159views more  BMCBI 2010»
13 years 6 months ago
Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
Alvaro J. González, Li Liao
TCBB
2008
126views more  TCBB 2008»
13 years 6 months ago
Graphical Models of Residue Coupling in Protein Families
Abstract-- Many statistical measures and algorithmic techniques have been proposed for studying residue coupling in protein families. Generally speaking, two residue positions are ...
John Thomas, Naren Ramakrishnan, Chris Bailey-Kell...
BMCBI
2006
137views more  BMCBI 2006»
13 years 6 months ago
A classification-based framework for predicting and analyzing gene regulatory response
Background: We have recently introduced a predictive framework for studying gene transcriptional regulation in simpler organisms using a novel supervised learning algorithm called...
Anshul Kundaje, Manuel Middendorf, Mihir Shah, Chr...
BMCBI
2008
100views more  BMCBI 2008»
13 years 6 months ago
PatternLab for proteomics: a tool for differential shotgun proteomics
Background: A goal of proteomics is to distinguish between states of a biological system by identifying protein expression differences. Liu et al. demonstrated a method to perform...
Paulo C. Carvalho, Juliana S. G. Fischer, Emily I....
IQ
2003
13 years 8 months ago
Data Quality in Genome Databases
: Genome databases store data about molecular biological entities such as genes, proteins, diseases, etc. The main purpose of creating and maintaining such databases in commercial ...
Heiko Müller, Felix Naumann