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» Learning Methods for DNA Binding in Computational Biology
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BMCBI
2008
132views more  BMCBI 2008»
13 years 7 months ago
Clustering ionic flow blockade toggles with a Mixture of HMMs
Background: Ionic current blockade signal processing, for use in nanopore detection, offers a promising new way to analyze single molecule properties with potential implications f...
Alexander G. Churbanov, Stephen Winters-Hilt
IPPS
2008
IEEE
14 years 1 months ago
Reducing the run-time of MCMC programs by multithreading on SMP architectures
The increasing availability of multi-core and multiprocessor architectures provides new opportunities for improving the performance of many computer simulations. Markov Chain Mont...
Jonathan M. R. Byrd, Stephen A. Jarvis, A. H. Bhal...
ICML
2005
IEEE
14 years 8 months ago
Predicting protein folds with structural repeats using a chain graph model
Protein fold recognition is a key step towards inferring the tertiary structures from amino-acid sequences. Complex folds such as those consisting of interacting structural repeat...
Yan Liu, Eric P. Xing, Jaime G. Carbonell
ISMB
2000
13 years 8 months ago
Analysis of Gene Expression Microarrays for Phenotype Classification
Several microarray technologies that monitor the level of expression of a large number of genes have recently emerged. Given DNA-microarray data for a set of cells characterized b...
Andrea Califano, Gustavo Stolovitzky, Yuhai Tu
BMCBI
2010
227views more  BMCBI 2010»
13 years 7 months ago
Accurate and efficient gp120 V3 loop structure based models for the determination of HIV-1 co-receptor usage
Background: HIV-1 targets human cells expressing both the CD4 receptor, which binds the viral envelope glycoprotein gp120, as well as either the CCR5 (R5) or CXCR4 (X4) co-recepto...
Majid Masso, Iosif I. Vaisman