1656 search results - page 322 / 332 » Learning and Consistency |
BMCBI
2010
13 years 7 months ago
2010
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
BMCBI
2008
13 years 7 months ago
2008
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
BIOINFORMATICS
2006
13 years 7 months ago
2006
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
BMCBI
2006
13 years 7 months ago
2006
Background: The structure of proteins may change as a result of the inherent flexibility of some protein regions. We develop and explore probabilistic machine learning methods for...
BMCBI
2006
13 years 7 months ago
2006
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...