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ICA
2010
Springer
13 years 11 months ago
Recovering Spikes from Noisy Neuronal Calcium Signals via Structured Sparse Approximation
Two-photon calcium imaging is an emerging experimental technique that enables the study of information processing within neural circuits in vivo. While the spatial resolution of th...
Eva L. Dyer, Marco F. Duarte, Don H. Johnson, Rich...
BMCBI
2010
84views more  BMCBI 2010»
13 years 10 months ago
A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis
Background: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to expl...
Benjamin A. Logsdon, Gabriel E. Hoffman, Jason G. ...
BMCBI
2008
109views more  BMCBI 2008»
13 years 10 months ago
ConStruct: Improved construction of RNA consensus structures
Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...
Andreas Wilm, Kornelia Linnenbrink, Gerhard Steger
BMCBI
2008
152views more  BMCBI 2008»
13 years 10 months ago
Predicting biological system objectives de novo from internal state measurements
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
CORR
2010
Springer
186views Education» more  CORR 2010»
13 years 10 months ago
A Homogeneous Reaction Rule Language for Complex Event Processing
Event-driven automation of reactive functionalities for complex event processing is an urgent need in today's distributed service-oriented architectures and Web-based event-d...
Adrian Paschke, Alexander Kozlenkov, Harold Boley