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BIOINFORMATICS
2010
13 years 9 months ago
2010
Motivation: The fruit fly (Drosophila melanogaster) is a commonly used model organism in biology. We are currently building a 3D digital atlas of the fruit fly larval nervous syst...
BMCBI
2010
13 years 9 months ago
2010
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
BMCBI
2010
13 years 9 months ago
2010
Background: Observed co-expression of a group of genes is frequently attributed to co-regulation by shared transcription factors. This assumption has led to the hypothesis that pr...
BMCBI
2010
13 years 9 months ago
2010
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
BMCBI
2010
13 years 9 months ago
2010
Background: Ab initio protein structure prediction methods generate numerous structural candidates, which are referred to as decoys. The decoy with the most number of neighbors of...