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BMCBI
2008
117views more  BMCBI 2008»
13 years 11 months ago
An iterative block-shifting approach to retention time alignment that preserves the shape and area of gas chromatography-mass sp
Background: Metabolomics, petroleum and biodiesel chemistry, biomarker discovery, and other fields which rely on high-resolution profiling of complex chemical mixtures generate da...
Minho Chae, Robert J. Shmookler Reis, John J. Thad...
BMCBI
2008
85views more  BMCBI 2008»
13 years 11 months ago
Wanted: unique names for unique atom positions. PDB-wide analysis of diastereotopic atom names of small molecules containing dip
Background: Biological chemistry is very stereospecific. Nonetheless, the diastereotopic oxygen atoms of diphosphate-containing molecules in the Protein Data Bank (PDB) are often ...
Christopher A. Bottoms, Dong Xu
BMCBI
2008
97views more  BMCBI 2008»
13 years 11 months ago
MCM-test: a fuzzy-set-theory-based approach to differential analysis of gene pathways
Background: Gene pathway can be defined as a group of genes that interact with each other to perform some biological processes. Along with the efforts to identify the individual g...
Lily R. Liang, Vinay Mandal, Yi Lu, Deepak Kumar
BMCBI
2008
116views more  BMCBI 2008»
13 years 11 months ago
Structuring an event ontology for disease outbreak detection
Background: This paper describes the design of an event ontology being developed for application in the machine understanding of infectious disease-related events reported in natu...
Ai Kawazoe, Hutchatai Chanlekha, Mika Shigematsu, ...
BMCBI
2006
126views more  BMCBI 2006»
13 years 10 months ago
OpWise: Operons aid the identification of differentially expressed genes in bacterial microarray experiments
Background: Differentially expressed genes are typically identified by analyzing the variation between replicate measurements. These procedures implicitly assume that there are no...
Morgan N. Price, Adam P. Arkin, Eric J. Alm
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