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BMCBI
2006
175views more  BMCBI 2006»
13 years 7 months ago
Parameter estimation for stiff equations of biosystems using radial basis function networks
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
Yoshiya Matsubara, Shinichi Kikuchi, Masahiro Sugi...
GPEM
2008
98views more  GPEM 2008»
13 years 7 months ago
Sporadic model building for efficiency enhancement of the hierarchical BOA
Efficiency enhancement techniques--such as parallelization and hybridization--are among the most important ingredients of practical applications of genetic and evolutionary algori...
Martin Pelikan, Kumara Sastry, David E. Goldberg
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
BMCBI
2006
124views more  BMCBI 2006»
13 years 7 months ago
Detection of divergent genes in microbial aCGH experiments
Background: Array-based comparative genome hybridization (aCGH) is a tool for rapid comparison of genomes from different bacterial strains. The purpose of such analysis is to dete...
Lars Snipen, Dirk Repsilber, Ludvig Nyquist, &Arin...
BMCBI
2006
137views more  BMCBI 2006»
13 years 7 months ago
GOPET: A tool for automated predictions of Gene Ontology terms
Background: Vast progress in sequencing projects has called for annotation on a large scale. A Number of methods have been developed to address this challenging task. These method...
Arunachalam Vinayagam, Coral del Val, Falk Schuber...