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» Learning to Predict Rare Events in Event Sequences
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BMCBI
2008
144views more  BMCBI 2008»
13 years 7 months ago
Local conservation scores without a priori assumptions on neutral substitution rates
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
Janis Dingel, Pavol Hanus, Niccolò Leonardi...
ALMOB
2006
135views more  ALMOB 2006»
13 years 7 months ago
P-value based visualization of codon usage data
Two important and not yet solved problems in bacterial genome research are the identification of horizontally transferred genes and the prediction of gene expression levels. Both ...
Peter Meinicke, Thomas Brodag, Wolfgang Florian Fr...
JCB
2008
90views more  JCB 2008»
13 years 7 months ago
A Simple Model of the Modular Structure of Transcriptional Regulation in Yeast
Resolving the general organizational principles that govern the interactions during transcriptional gene regulation has great relevance for understanding disease progression, biof...
Vladimir Filkov, Nameeta Shah
BMCBI
2005
87views more  BMCBI 2005»
13 years 7 months ago
ProfNet, a method to derive profile-profile alignment scoring functions that improves the alignments of distantly related protei
Background: Profile-profile methods have been used for some years now to detect and align homologous proteins. The best such methods use information from the background distributi...
Tomas Ohlson, Arne Elofsson
SIGSOFT
2009
ACM
14 years 8 months ago
Improving bug triage with bug tossing graphs
A bug report is typically assigned to a single developer who is then responsible for fixing the bug. In Mozilla and Eclipse, between 37%-44% of bug reports are "tossed" ...
Gaeul Jeong, Sunghun Kim, Thomas Zimmermann