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BMCBI
2010
140views more  BMCBI 2010»
13 years 8 months ago
Quantification and deconvolution of asymmetric LC-MS peaks using the bi-Gaussian mixture model and statistical model selection
Background: Liquid chromatography-mass spectrometry (LC-MS) is one of the major techniques for the quantification of metabolites in complex biological samples. Peak modeling is on...
Tianwei Yu, Hesen Peng
BMCBI
2010
139views more  BMCBI 2010»
13 years 8 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
CGF
2010
189views more  CGF 2010»
13 years 8 months ago
Space-in-Time and Time-in-Space Self-Organizing Maps for Exploring Spatiotemporal Patterns
Spatiotemporal data pose serious challenges to analysts in geographic and other domains. Owing to the complexity of the geospatial and temporal components, this kind of data canno...
Gennady L. Andrienko, Natalia V. Andrienko, Sebast...
BMCBI
2005
112views more  BMCBI 2005»
13 years 7 months ago
Integration of the Gene Ontology into an object-oriented architecture
Background: To standardize gene product descriptions, a formal vocabulary defined as the Gene Ontology (GO) has been developed. GO terms have been categorized into biological proc...
Daniel Shegogue, W. Jim Zheng
CORR
2002
Springer
96views Education» more  CORR 2002»
13 years 7 months ago
The Sketch of a Polymorphic Symphony
In previous work, we have introduced functional strategies, that is, first-class generic functions that can traverse into terms of any type while mixing uniform and type-specific ...
Ralf Lämmel