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BMCBI
2008
218views more  BMCBI 2008»
13 years 9 months ago
LOSITAN: A workbench to detect molecular adaptation based on a Fst-outlier method
Background: Testing for selection is becoming one of the most important steps in the analysis of multilocus population genetics data sets. Existing applications are difficult to u...
Tiago Antao, Ana Lopes, Ricardo J. Lopes, Albano B...
BMCBI
2008
159views more  BMCBI 2008»
13 years 9 months ago
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via log
Background: Growing interest on biological pathways has called for new statistical methods for modeling and testing a genetic pathway effect on a health outcome. The fact that gen...
Dawei Liu, Debashis Ghosh, Xihong Lin
BMCBI
2008
108views more  BMCBI 2008»
13 years 9 months ago
New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic backgroun
Background: Few genetic factors predisposing to the sporadic form of amyotrophic lateral sclerosis (ALS) have been identified, but the pathology itself seems to be a true multifac...
Silvana Penco, Massimo Buscema, Maria Cristina Pat...
CGF
2010
146views more  CGF 2010»
13 years 9 months ago
Pathline: A Tool For Comparative Functional Genomics
Biologists pioneering the new field of comparative functional genomics attempt to infer the mechanisms of gene regulation by looking for similarities and differences of gene activ...
Miriah D. Meyer, Bang Wong, Mark P. Styczynski, Ta...
CORR
2010
Springer
152views Education» more  CORR 2010»
13 years 9 months ago
Microlocal Analysis of the Geometric Separation Problem
Image data are often composed of two or more geometrically distinct constituents; in galaxy catalogs, for instance, one sees a mixture of pointlike structures (galaxy supercluster...
David L. Donoho, Gitta Kutyniok