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BMCBI
2010
112views more  BMCBI 2010»
13 years 7 months ago
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
Andrew J. Bordner
BMCBI
2010
111views more  BMCBI 2010»
13 years 7 months ago
Protein sequences classification by means of feature extraction with substitution matrices
Background: This paper deals with the preprocessing of protein sequences for supervised classification. Motif extraction is one way to address that task. It has been largely used ...
Rabie Saidi, Mondher Maddouri, Engelbert Mephu Ngu...
BMCBI
2010
178views more  BMCBI 2010»
13 years 7 months ago
Applications of a formal approach to decipher discrete genetic networks
Background: A growing demand for tools to assist the building and analysis of biological networks exists in systems biology. We argue that the use of a formal approach is relevant...
Fabien Corblin, Eric Fanchon, Laurent Trilling
ENVSOFT
2008
175views more  ENVSOFT 2008»
13 years 7 months ago
Automated regression-based statistical downscaling tool
Many impact studies require climate change information at a finer resolution than that provided by Global Climate Models (GCMs). In the last 10 years, downscaling techniques, both...
Masoud Hessami, Philippe Gachon, Taha B. M. J. Oua...
BMCBI
2006
134views more  BMCBI 2006»
13 years 7 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...