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BMCBI
2008
98views more  BMCBI 2008»
13 years 7 months ago
Empirical Bayes models for multiple probe type microarrays at the probe level
Background: When analyzing microarray data a primary objective is often to find differentially expressed genes. With empirical Bayes and penalized t-tests the sample variances are...
Magnus Åstrand, Petter Mostad, Mats Rudemo
BMCBI
2008
129views more  BMCBI 2008»
13 years 7 months ago
A unified approach to false discovery rate estimation
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
Korbinian Strimmer
BMCBI
2010
243views more  BMCBI 2010»
13 years 7 months ago
Comparative study of unsupervised dimension reduction techniques for the visualization of microarray gene expression data
Background: Visualization of DNA microarray data in two or three dimensional spaces is an important exploratory analysis step in order to detect quality issues or to generate new ...
Christoph Bartenhagen, Hans-Ulrich Klein, Christia...
BMCBI
2008
125views more  BMCBI 2008»
13 years 7 months ago
A fast algorithm for the multiple genome rearrangement problem with weighted reversals and transpositions
Background: Due to recent progress in genome sequencing, more and more data for phylogenetic reconstruction based on rearrangement distances between genomes become available. Howe...
Martin Bader, Mohamed Ibrahim Abouelhoda, Enno Ohl...
CAD
2008
Springer
13 years 7 months ago
Structure-oriented contour representation and matching for engineering shapes
Conventional shape matching for engineering models primarily considers rigid shape similarity. They do not seek global shape similarity while considering large local deformations....
Suyu Hou, Karthik Ramani