This paper proposes a hybrid genetic algorithm for multiple sequence alignment. The algorithm evolves guide sequences and aligns input sequences based on the guide sequences. It a...
Wire routing in a VLSI chip often requires minimization of wire-length as well as the number of intersections among multiple nets. Such an optimization problem is computationally ...
Rajeev Kumar, Pramod Kumar Singh, Bhargab B. Bhatt...
Abstract. Researchers have focused on assessing the quality of search algorithms by measuring effort, number of mistakes, runtime distributions and other characteristics. In this p...
In this paper, we perform a comparative study of different heuristics used to design combinational logic circuits. The use of local search hybridized with a genetic algorithm and ...
Carlos A. Coello Coello, Enrique Alba, Gabriel Luq...
Mixtures of Gaussians are among the most fundamental and widely used statistical models. Current techniques for learning such mixtures from data are local search heuristics with w...