Abstract. It is estimated that 20% of genes in the human genome encode for integral membrane proteins (IMPs) and some estimates are much higher. IMPs control a broad range of event...
Background: The activity of proteins within the cell is characterized by their motions, flexibility, interactions or even the particularly intriguing case of partially unfolded st...
A novel approach for similarity search on the protein structure databases is proposed. PADS (Protein Alignment by Directional shape Signatures) incorporates the three dimensional ...
S. Alireza Aghili, Divyakant Agrawal, Amr El Abbad...
Background: Automated protein function prediction methods are the only practical approach for assigning functions to genes obtained from model organisms. Many of the previously re...
Jaehee Jung, Gangman Yi, Serenella A. Sukno, Micha...
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...