36 search results - page 5 / 8 » Local sequence alignments with monotonic gap penalties |
BMCBI
2008
13 years 7 months ago
2008
Background: Identification of RNA homologs within genomic stretches is difficult when pairwise sequence identity is low or unalignable flanking residues are present. In both cases...
BMCBI
2010
13 years 7 months ago
2010
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
BMCBI
2006
13 years 7 months ago
2006
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
BMCBI
2006
13 years 7 months ago
2006
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
BMCBI
2011
12 years 11 months ago
2011
Background: Pairwise sequence alignment methods are widely used in biological research. The increasing number of sequences is perceived as one of the upcoming challenges for seque...