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BMCBI
2008
75views more  BMCBI 2008»
13 years 7 months ago
Re-searcher: a system for recurrent detection of homologous protein sequences
Background: Sequence searches are routinely employed to detect and annotate related proteins. However, a rapid growth of databases necessitates a frequent repetition of sequence s...
Valdemaras Repsys, Mindaugas Margelevicius, Ceslov...
JCB
2002
116views more  JCB 2002»
13 years 7 months ago
A Novel Approach to Remote Homology Detection: Jumping Alignments
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...
Rainer Spang, Marc Rehmsmeier, Jens Stoye
TCBB
2008
138views more  TCBB 2008»
13 years 7 months ago
PairProSVM: Protein Subcellular Localization Based on Local Pairwise Profile Alignment and SVM
The subcellular locations of proteins are important functional annotations. An effective and reliable subcellular localization method is necessary for proteomics research. This pap...
Man-Wai Mak, Jian Guo, Sun-Yuan Kung
COCOON
2010
Springer
14 years 16 days ago
Tracking a Generator by Persistence
The persistent homology provides a mathematical tool to describe “features” in a principled manner. The persistence algorithm proposed by Edelsbrunner et al. [9] can compute n...
Oleksiy Busaryev, Tamal K. Dey, Yusu Wang
CIKM
2008
Springer
13 years 9 months ago
Pairwise statistical significance of local sequence alignment using multiple parameter sets
Background: Accurate estimation of statistical significance of a pairwise alignment is an important problem in sequence comparison. Recently, a comparative study of pairwise stati...
Ankit Agrawal, Xiaoqiu Huang