Background: The availability of complete genomic sequences for hundreds of organisms promises to make obtaining genome-wide estimates of substitution rates, selective constraints ...
Amy Egan, Anup Mahurkar, Jonathan Crabtree, Jonath...
Motivation: Sigma factors regulate the expression of genes in Bacillus subtilis at the transcriptional level. First we assess the ability of currently available gene regulatory ne...
Michiel J. L. de Hoon, Yuko Makita, Seiya Imoto, K...
Abstract. Metagenomics is the study of microbial communities sampled directly from their natural environment, without prior culturing. Among the computational tools recently develo...
Background: Owing to the rapid expansion of RNA structure databases in recent years, efficient methods for structure comparison are in demand for function prediction and evolution...
The complexity of the global organization and internal structures of motifs in higher eukaryotic organisms raises significant challenges for motif detection techniques. To achiev...
Eric P. Xing, Wei Wu, Michael I. Jordan, Richard M...