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BMCBI
2010
102views more  BMCBI 2010»
13 years 7 months ago
SAMPLEX: Automatic mapping of perturbed and unperturbed regions of proteins and complexes
Background: The activity of proteins within the cell is characterized by their motions, flexibility, interactions or even the particularly intriguing case of partially unfolded st...
Mickaël Krzeminski, Karine Loth, Rolf Boelens...
BMCBI
2008
154views more  BMCBI 2008»
13 years 7 months ago
Bayesian models and meta analysis for multiple tissue gene expression data following corticosteroid administration
Background: This paper addresses key biological problems and statistical issues in the analysis of large gene expression data sets that describe systemic temporal response cascade...
Yulan Liang, Arpad Kelemen
BMCBI
2010
152views more  BMCBI 2010»
13 years 7 months ago
Comparative study of discretization methods of microarray data for inferring transcriptional regulatory networks
Background: Microarray data discretization is a basic preprocess for many algorithms of gene regulatory network inference. Some common discretization methods in informatics are us...
Yong Li, Lili Liu, Xi Bai, Hua Cai, Wei Ji, Dianji...
BMCBI
2010
133views more  BMCBI 2010»
13 years 7 months ago
Integrated prediction of one-dimensional structural features and their relationships with conformational flexibility in helical
Background: Many structural properties such as solvent accessibility, dihedral angles and helix-helix contacts can be assigned to each residue in a membrane protein. Independent s...
Shandar Ahmad, Yumlembam Hemjit Singh, Yogesh Paud...
BMCBI
2008
130views more  BMCBI 2008»
13 years 7 months ago
Function approximation approach to the inference of reduced NGnet models of genetic networks
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
Shuhei Kimura, Katsuki Sonoda, Soichiro Yamane, Hi...
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