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BIOINFORMATICS
2007
151views more  BIOINFORMATICS 2007»
13 years 9 months ago
A new protein-protein docking scoring function based on interface residue properties
Motivation: Protein–protein complexes are known to play key roles in many cellular processes. However, they are often not accessible to experimental study because of their low s...
Julie Bernauer, Jérôme Azé, Jo...
BMCBI
2008
145views more  BMCBI 2008»
13 years 9 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
CANDC
2004
ACM
13 years 9 months ago
The iProClass integrated database for protein functional analysis
Increasingly, scientists have begun to tackle gene functions and other complex regulatory processes by studying organisms at the global scales for various levels of biological org...
Cathy H. Wu, Hongzhan Huang, Anastasia N. Nikolska...
BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
14 years 4 months ago
Application of Kernel Functions for Accurate Similarity Search in Large Chemical Databases
Background: Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screeni...
Xiaohong Wang, Jun Huan, Aaron M. Smalter, Gerald ...
ICFP
2005
ACM
14 years 9 months ago
PolyAML: a polymorphic aspect-oriented functional programming language
This paper defines PolyAML, a typed functional, aspect-oriented programming language. The main contribution of PolyAML is the seamless integration of polymorphism, run-time type a...
Daniel S. Dantas, David Walker, Geoffrey Washburn,...