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» MDGA: motif discovery using a genetic algorithm
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ISMB
1994
13 years 9 months ago
High Speed Pattern Matching in Genetic Data Base with Reconfigurable Hardware
Homologydetection in large data bases is probably the most time consuming operation in molecular genetic computing systems. Moreover, the progresses made all around the world conc...
Eric Lemoine, Joël Quinqueton, Jean Sallantin
CSB
2005
IEEE
168views Bioinformatics» more  CSB 2005»
14 years 1 months ago
cis-Regulatory Element Prediction in Mammalian Genomes
The identification of cis-regulatory elements and modules is an important step in understanding the regulation of genes. We have developed a pipeline capable of running multiple m...
Asim S. Siddiqui, Gordon Robertson, Misha Bilenky,...
IIS
2004
13 years 9 months ago
Application of evolutionary computing to conformational analysis
In this paper we report new results concerning use of genetic algorithms in conformational analysis, field of pharmacy related to discovery and design of new drugs. The goal is to ...
Aleksander Wawer, Franciszek Seredynski, Pascal Bo...
KDD
2002
ACM
125views Data Mining» more  KDD 2002»
14 years 8 months ago
Pattern discovery in sequences under a Markov assumption
In this paper we investigate the general problem of discovering recurrent patterns that are embedded in categorical sequences. An important real-world problem of this nature is mo...
Darya Chudova, Padhraic Smyth
BMCBI
2010
121views more  BMCBI 2010»
13 years 5 months ago
Computing DNA duplex instability profiles efficiently with a two-state model: trends of promoters and binding sites
Background: DNA instability profiles have been used recently for predicting the transcriptional start site and the location of core promoters, and to gain insight into promoter ac...
Miriam R. Kantorovitz, Zoi Rapti, Vladimir Gelev, ...