Sciweavers

125 search results - page 7 / 25
» MDGA: motif discovery using a genetic algorithm
Sort
View
BMCBI
2006
113views more  BMCBI 2006»
13 years 8 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida
BMCBI
2006
87views more  BMCBI 2006»
13 years 8 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
BMCBI
2006
141views more  BMCBI 2006»
13 years 8 months ago
Identification of consensus RNA secondary structures using suffix arrays
Background: The identification of a consensus RNA motif often consists in finding a conserved secondary structure with minimum free energy in an ensemble of aligned sequences. How...
Mohammad Anwar, Truong Nguyen, Marcel Turcotte
CSB
2003
IEEE
14 years 1 months ago
Haplotype Motifs: An Algorithmic Approach to Locating Evolutionarily Conserved Patterns in Haploid Sequences
The promise of plentiful data on common human genetic variations has given hope that we will be able to uncover genetic factors behind common diseases that have proven difficult ...
Russell Schwartz
JCB
2007
118views more  JCB 2007»
13 years 7 months ago
Discovering Topological Motifs Using a Compact Notation
Discovering topological motifs or common topologies in one or more graphs is an important as well as an interesting problem. It had been classically viewed as the subgraph isomorp...
Laxmi Parida