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BMCBI
2006
159views more  BMCBI 2006»
13 years 7 months ago
Prediction of protein continuum secondary structure with probabilistic models based on NMR solved structures
Background: The structure of proteins may change as a result of the inherent flexibility of some protein regions. We develop and explore probabilistic machine learning methods for...
Mikael Bodén, Zheng Yuan, Timothy L. Bailey
ML
2002
ACM
178views Machine Learning» more  ML 2002»
13 years 7 months ago
Metric-Based Methods for Adaptive Model Selection and Regularization
We present a general approach to model selection and regularization that exploits unlabeled data to adaptively control hypothesis complexity in supervised learning tasks. The idea ...
Dale Schuurmans, Finnegan Southey
ICML
2009
IEEE
14 years 2 months ago
Decision tree and instance-based learning for label ranking
The label ranking problem consists of learning a model that maps instances to total orders over a finite set of predefined labels. This paper introduces new methods for label ra...
Weiwei Cheng, Jens C. Huhn, Eyke Hüllermeier
JBCB
2010
138views more  JBCB 2010»
13 years 2 months ago
Hierarchical Classification of Gene Ontology Terms Using the Gostruct Method
Protein function prediction is an active area of research in bioinformatics. And yet, transfer of annotation on the basis of sequence or structural similarity remains widely used ...
Artem Sokolov, Asa Ben-Hur
MLDM
2009
Springer
14 years 2 months ago
Drift-Aware Ensemble Regression
Abstract. Regression models are often required for controlling production processes by predicting parameter values. However, the implicit assumption of standard regression techniqu...
Frank Rosenthal, Peter Benjamin Volk, Martin Hahma...