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» Machine learning methods for metabolic pathway prediction
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BMCBI
2010
165views more  BMCBI 2010»
13 years 9 months ago
MTar: a computational microRNA target prediction architecture for human transcriptome
Background: MicroRNAs (miRNAs) play an essential task in gene regulatory networks by inhibiting the expression of target mRNAs. As their mRNA targets are genes involved in importa...
Vinod Chandra, Reshmi Girijadevi, Achuthsankar S. ...
ICML
2004
IEEE
14 years 10 months ago
Kernel conditional random fields: representation and clique selection
Kernel conditional random fields (KCRFs) are introduced as a framework for discriminative modeling of graph-structured data. A representer theorem for conditional graphical models...
John D. Lafferty, Xiaojin Zhu, Yan Liu
ICML
2007
IEEE
14 years 10 months ago
Gradient boosting for kernelized output spaces
A general framework is proposed for gradient boosting in supervised learning problems where the loss function is defined using a kernel over the output space. It extends boosting ...
Florence d'Alché-Buc, Louis Wehenkel, Pierr...
ICML
2003
IEEE
14 years 10 months ago
Optimization with EM and Expectation-Conjugate-Gradient
We show a close relationship between the Expectation - Maximization (EM) algorithm and direct optimization algorithms such as gradientbased methods for parameter learning. We iden...
Ruslan Salakhutdinov, Sam T. Roweis, Zoubin Ghahra...
BMCBI
2010
127views more  BMCBI 2010»
13 years 9 months ago
Computational prediction of type III secreted proteins from gram-negative bacteria
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...